| icon | info | gamerscore |
|---|---|---|
| Safecracker Crack all safes. | 75 | |
| It's Only Business Eliminate Hyman Roth. | 75 | |
| Bag Man Heist each bank once. | 20 | |
| Last Family Standing Eliminate all five rival families. | 50 | |
| Organized Crime Control all crime rings. | 75 | |
| Ambush Eliminate four rival families. | 40 | |
| Bank Job Heist your first bank. | 5 | |
| Shakedown Control all extortable businesses. | 25 | |
| CIA? DOA Kill Henry Mitchell. | 25 | |
| Torch The Joint Send your men to bomb a venue from the Don's View. | 5 | |
| This Thing Of Ours Recruit a full family tree. | 25 | |
| Second In Command Promote one of your made men to Underboss. | 15 | |
| 750 Sleeping With The Fishes Kill 750 mobsters. | 30 | |
| Paying Tribute Unlock all safehouses. | 10 | |
| Modified Firepower Find a level 3 firearm upgrade. | 20 | |
| Vendetta Eliminate three rival families. | 30 | |
| Fortified Venue Max out all guards at a venue. | 5 | |
| Five Crime Rings Control five crime rings. | 50 | |
| Double Crossed Eliminate two rival families. | 20 | |
| 500 Empty Suits Kill 500 mobsters. | 25 | |
| Contract Killer Eliminate 5 made men with the appropriate kill condition. | 15 | |
| The Counselor Accept Tom Hagen as your Consigliere. | 25 | |
| Three Crime Rings Control three crime rings. | 40 | |
| 250 Iced Kill 250 mobsters. | 20 | |
| Right Hand Man Promote one of your made men to Capo. | 10 | |
| Full Of Lead Kill 150 mobsters only using firearms. | 10 | |
| BlackHand Brutality Kill 25 mobsters only using BlackHand attacks. | 10 | |
| It's Not Personal Eliminate a rival family by successfully bombing their compound. | 20 | |
| Gun Smuggler Find a level 2 firearm upgrade. | 10 | |
| Lockpicker Crack five safes. | 5 | |
| 100 Whacked Kill 100 mobsters. | 15 | |
| Enforcer Complete 10 execution styles. | 15 | |
| Let Me Upgrade You Upgrade one of your made men's skills or weapons. | 5 | |
| First Crime Ring Control one crime ring. | 15 | |
| Pulling The Strings Send your men to attack a venue from the Don's View. | 5 | |
| 25 Massacred Kill 25 mobsters. | 10 | |
| Getting Made Recruit your first soldier. | 5 | |
| MobFace Create a mobster using MobFace. | 5 | |
| Welcome To The Gun Show Collect all level 2 and 3 firearm upgrades. | 30 | |
| Accept This As A Gift Earn one of each favor. | 30 | |
| Executions In Style Complete all execution styles. | 75 |
