| icon | info | gamerscore |
|---|---|---|
 | Human Completed the game on Human difficulty | 25 |
 | Hero Completed the game on Hero difficulty | 40 |
 | Super Hero Completed the game on Super Hero difficulty | 80 |
 | Bookworm Collected all Spider-Man comic books | 25 |
 | Lover Retrieved all parts of Black Cat's journal | 15 |
 | Special Agent Retrieved all parts of Menken's journal | 15 |
 | Investigator Retrieved all parts of Detective's journal | 15 |
 | I'm on a Roll Achieved a combo streak of 42 | 15 |
 | Stay Down! Performed 15 signature moves | 10 |
 | Breaker Destroyed 20 body armors | 10 |
 | Know Your Enemies Unlocked all character bios | 15 |
 | Reporter Completed all photo challenges | 15 |
 | All Tied Up Defeated 50 enemies by performing stealth takedowns | 25 |
 | Hunter of Killers Photographed all Cletus Kasady symbols | 30 |
 | Drop It! Disarmed 50 enemies | 30 |
 | Shocking! Defeated Shocker | 30 |
 | The Hunter, Hunted Defeated Kraven | 30 |
 | Lovers' Quarrel Defeated Black Cat | 20 |
 | Is It Over? Defeated Cletus Kasady | 20 |
 | You Are Under Arrest Defeated Kingpin | 20 |
 | The Green Goblin Defeated Green Goblin | 30 |
 | Switch Off Defeated Electro | 30 |
 | Now It Is Over Defeated Carnage | 30 |
 | Fashionista Unlocked all suits | 20 |
 | Infiltration Completed all hideouts | 20 |
 | Luchador! Completed all combat challenges | 15 |
 | Can't Hit Me Achieved 30 multidodges | 20 |
 | Timing Is Everything Achieved 100 critical hits | 20 |
 | Lightweight Champion Defeated 100 enemies | 20 |
 | Middleweight Champion Defeated 300 enemies | 20 |
 | Heavyweight Champion Defeated 500 enemies | 20 |
 | Hero of the People Saved 50 civilians | 30 |
 | Ultimate Spider-Man Reached maximum levels for all suits | 30 |
 | State of the Art Unlocked all concept art | 20 |
 | True Hero Heroism to the maximum | 20 |
 | Enforcer Completed 10 deadlock situations | 15 |
 | Fireman Completed 10 building on fire situations | 15 |
 | Guardian Angel Completed 10 rescue situations | 15 |
 | Vigilante Completed 10 petty crime situations | 15 |
 | Fast-Tracker Completed 5 races | 15 |
 | Master of the Web Performed 50 signature moves | 20 |
 | Friendly Fire Damaged Carnage with fire at least 3 times before defeating him | 15 |
 | Shotgun Acquired the Seismic Blast ability | 10 |
 | Disintegrator Acquired the ionic web | 10 |
 | Aerial Break Destroyed any armored enemy using Web-Strike | 20 |
 | Sneaky Completed a hideout without being spotted | 20 |
