| icon | info | RA score |
|---|---|---|
 | If You Can't Take the Heat... Complete "Feel the Burn" | 5points |
 | Welcome to NYC Complete "Life in the Big City" | 2points |
 | Bomber Man Complete "H-Bombers Shakedown" | 4points |
 | "Bugle Blown to Smithereens" Complete "Breaking News" | 5points |
 | Connors' Reptiles Complete "Cold-Blooded Candids" | 5points |
 | The New Goblin Complete "A Harry Situation" | 5points |
 | Trial Separation Complete "Crank Collar" | 5points |
 | Night of the Lizard Complete "Reptilian Rampage" | 5points |
 | Cool in the Summer, Warm in the Winter Complete "Escape Under New York" | 5points |
 | Kraven's First Hunt Complete "Hunter or Hunted?" | 5points |
 | Natural Selection Complete "Rumble Down Under" | 10points |
 | Hunting for Dragon Tails Complete "The Unusual Suspects" | 5points |
 | Kraven's Second Hunt Complete "The Cornered Animal" | 5points |
 | World's Biggest Lizard Complete "My, What Big Teeth You Have" | 10points |
 | City Lizard Complete "Lizard Leftovers" | 5points |
 | Neogenic Nightmare Complete "Wild Bat Chase" | 5points |
 | Need... More... PLASMA! Complete "By the Dawn's Early Light" | 5points |
 | Enter Shriek Complete "Crowd Control" | 10points |
 | Wasting the Waste Tribe Complete "Tribal Takedown" | 5points |
 | You Were Expecting, Maybe, Belo Lugosi? Complete "Family Reunion" | 10points |
 | Bully Maguire Strikes Again Complete "Stunt Double" | 5points |
 | It's Time to Pay, Marko! Complete "My Way or the Subway" | 10points |
 | How’d That Get in There? Complete "My Dinner with MJ" | 3points |
 | The Sinister Two Complete "The Final Showdown" | 25points |
 | The Spider Who Collects Spiders Collect all 50 Spider Emblems | 25points |
 | Meteor Man Collect all 100 Meteorite Fragments | 50points |
 | Superior Spider-Man Purchase all Hero Upgrades | 25points |
 | The Fastest Spider Alive Complete every Trick Race with the rank of Super Hero | 25points |
 | Speed Defusal Deactivate all 7 bombs in "Breaking News" in under 55 seconds | 10points |
 | Maybe Not So Harry after All Complete "A Harry Situation" without taking damage more than 3 times | 10points |
 | Not a Drill! Escape the giant drill in "Hunter or Hunted?" without taking damage | 10points |
 | Sponsored by Hostess [City Alert] Help deliver some delicious Fruit Pies | 3points |
 | The Amazing Spider Guy [City Alert] Perform some stunts for a tourist's camera | 3points |
 | Police Crackdown! Reduce ALL gang activity to 0% | 25points |
 | Apocalypse Anarchy Reduce Apocalypse gang activity to 0% | 10points |
 | H-Bombers Offensive Reduce H-Bombers gang activity to 0% | 10points |
 | Dragon Tails Lashing Reduce Dragon Tails gang activity to 0% | 10points |
 | Waste Tribe Warpath Reduce Waste Tribe gang activity to 0% | 10points |
 | Combo Man Keep a combo going for 20 hits or more | 10points |
 | Sensational Combo Man Deal 2000 damage or more during a combo and earn a "SENSATIONAL" score | 25points |
 | Ace Photographer Take all 35 Villain Photos | 25points |
 | A Hands-On Approach Defeat Venom for the first time in "The Final Showdown" with at least 2 minutes left on the clock | 25points |
 | Toro! Toro! Destroy three generators in "My, What Big Teeth You Have" without taking damage | 10points |
 | It's Morbin' Time! Survive until dawn in "By the Dawn's Early Light" without deploying more than 3 web traps | 10points |
 | A Shrieking Good Time Defeat Shriek in "Crowd Control without pressing the X button or taking damage more than 5 times | 10points |
 | The Spectacular Completionist Reach 100% completion percentage | 100points |
 | Kindness Is Its Own Reward [City Alert] Help find a lost child | 2points |
 | Bugle Boy [City Alert] Escort a journalist to an important news story | 3points |
 | Healthy Spidey Purchase all Health Upgrades | 10points |
 | Speedy Spidey Purchase all Speed Upgrades | 10points |
