| icon | info | gamerscore |
|---|---|---|
| Mega Tourist Took a photograph from the tallest building in the city. | 10 | |
| Web Swinger Swung a total of 10 miles. | 20 | |
| Mega Web Swinger Swung a total of 200 miles. | 30 | |
| Police Corporal Complete all Petty Theft missions. | 30 | |
| Pole Swinger Swung on 50 poles. | 10 | |
| Police Officer Completed all Crime Spree missions. | 30 | |
| Fast Swinger Swung at the maximum swing speed of 200 miles per hour. | 20 | |
| Splat Master 2007 Splatted into the ground 25 times. | 20 | |
| Spider-Man Completed all missions. | 50 | |
| Mary Jane Thriller Completed all Mary Jane thrill rides. | 20 | |
| Cold Blooded Super Master Completed all Connors missions. | 30 | |
| A Dark Reward Unlocked Black-Suited Spider-Man. | 20 | |
| Eddie Brock Defeated Venom. | 40 | |
| Aleksei Sytsevich Defeated Rhino. | 30 | |
| Wilson Fisk Defeated Kingpin. | 30 | |
| Police Detective Completed 25 random city missions. | 30 | |
| Sergei Kravinoff Defeated Kraven. | 30 | |
| Flint Marko Defeated Sandman. | 30 | |
| Luke Carlyle Defeated Carlyle. | 30 | |
| Police Sergeant Completed all Bank Robbery missions. | 30 | |
| Deputy Completed all DeWolfe missions. | 30 | |
| Macdonald Gargan Rescued Scorpion. | 40 | |
| Web Slinger Webbed up 25 enemies. | 20 | |
| Harry Osborn Defeated New Goblin. | 30 | |
| Hitch Hiker Rode a car or truck for 5 miles. | 20 | |
| Collateral Damage Destroyed 25 objects. | 10 | |
| Shutterbug Completed all Daily Bugle photo missions. | 20 | |
| Master Web Swinger Swung a total of 50 miles. | 20 | |
| Curtis Connors Defeated Lizard. | 30 |
