| icon | info |
|---|---|
 | Platinum Trophy Unlock all trophies |
 | Every Knee Will Bend Finish the game on Normal Mode with any character |
 | Every Head Will Bow Finish the game on Hard Mode with any character |
 | Every Tongue Will Confess Finish the game on Must Die Mode with any character |
 | Barehand Beauty Finish the game on any difficulty with Trish |
 | A Secret Revealed Complete a Secret Mission |
 | First Blood Pass 1000 levels in Bloody Palace Mode |
 | Blood Letting Pass 5000 levels in Bloody Palace Mode |
 | Over 9000! Pass 9000 levels in Bloody Palace Mode |
 | Highest Honor Achieve an S Rank on any Mission with Dante |
 | The Sky's The Limit Achieve an S Rank on any Mission with Lucia |
 | Vita Maxima Max out Health Bar with any character |
 | Magica Maxima Max out Devil Trigger Gauge with any character |
 | Caeruleus Diabolus Collect 12 Blue Orb fragments (Dante/Lucia) |
 | Two Heads are Better Than One Defeat Tartarussian |
 | Monkeying Around Defeat Orangguerra |
 | No Joke Defeat Jokatgulm |
 | Sin City Defeat Nefasturris |
 | Deep One Defeat Tateobesu |
 | That's A Big Mother... Defeat Noctpteran |
 | Hungry Like the Wolves Defeat Bolverk |
 | Ball 'n Chain Defeat Plutonian |
 | Not Just Any Ordinary Human Defeat Phantom |
 | Never Forget a Face Defeat Trismagia |
 | Extinguished Defeat the final boss with either Dante or Lucia |
 | Stylish! Perform an S Rank Combo using Dante |
 | En Vogue Perform an S Rank Combo using Lucia |
 | Armed and Dangerous Reach Level 3 on any Sword with Lucia |
 | Arms Race Reach Level 3 on any Gun with Dante |
 | Like A Hot Knife Through Butter Reach Level 3 on all Swords with Dante |
 | To The Max Reach Level 3 on all Arsenals with Lucia |
 | Full Armory Collect all Swords with Dante |
 | Check Out My Collection Collect all Arsenals with Lucia |
 | Take Heart, Lucia Collect all Devil Hearts with Lucia |
